Enviar artigo por via de e-mail Local Treatment of Local Staphylococcal Infection with Complex Preparations Based on Metal Nanoparticles in the Experiment
- Autores: Babushkina I.V.1, Mamonova I.A.1, Ulyanov V.Y.1
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Afiliações:
- Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation
- Edição: Volume 167, Nº 6 (2019)
- Páginas: 784-786
- Seção: Biotechnologies
- URL: https://journal-vniispk.ru/0007-4888/article/view/242115
- DOI: https://doi.org/10.1007/s10517-019-04622-w
- ID: 242115
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Resumo
Antibacterial activity of powdered preparations based on copper and silver nanoparticles was compared with activity of the reference preparation Baneocin on the model of local staphylococcal infection in white rats. The developed preparations exhibited pronounced antibacterial activity against methicillin-resistant S. epidermidis strains in vivo significantly (p<0.001) exceeding that of Baneocin, reduced microbial contamination of the wound on day 5 of study by 2 lg and more in comparison with bacterial load before treatment, and provided effective decontamination of the wound within 7-10 days.
Sobre autores
I. Babushkina
Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: 10051968@mail.ru
Rússia, Saratov
I. Mamonova
Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation
Email: 10051968@mail.ru
Rússia, Saratov
V. Ulyanov
Research Institute of Traumatology, Orthopedics, and Neurosurgery, V. I. Razumovsky Saratov Medical University, Ministry of Health of the Russian Federation
Email: 10051968@mail.ru
Rússia, Saratov
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