Отправить статью по E-mail Antitumor Effects of Sorbus aucuparia L. Extract Highly Saturated with Anthocyans and Their Mechanisms
- Авторы: Razina T.G.1, Zueva E.P.1, Ulrich A.V.1, Rybalkina O.Y.1,2, Chaikovskii A.V.1, Isaikina N.V.3, Kalinkina G.I.3, Zhdanov V.V.1, Zyuz’kov G.N.1,2
-
Учреждения:
- E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
- National Research Tomsk State University
- Siberian State Medical University, Ministry of Health of the Russian Federation
- Выпуск: Том 162, № 1 (2016)
- Страницы: 93-97
- Раздел: Article
- URL: https://journal-vniispk.ru/0007-4888/article/view/237943
- DOI: https://doi.org/10.1007/s10517-016-3554-4
- ID: 237943
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
The effects of Fructus Sorbi aucupariae extract, originally saturated with anthocyans, on the development of Lewis lung carcinoma and B-16 melanoma in C57Bl/6 mice and the efficiency of cyclophosphamide treatment were studied. Antitumor activity of the extract and potentiation of the antimetastatic activity of the cytostatic were demonstrated. Studies on melanoma B-16 model revealed an increase in the counts of stromal progenitor cells in the tumor node and their accelerated maturation after treatment with the extract. No effects towards the tumor stem and committed cells were detected.
Об авторах
T. Razina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Автор, ответственный за переписку.
Email: razinatg22@gmail.com
Россия, Tomsk
E. Zueva
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: razinatg22@gmail.com
Россия, Tomsk
A. Ulrich
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: razinatg22@gmail.com
Россия, Tomsk
O. Rybalkina
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine; National Research Tomsk State University
Email: razinatg22@gmail.com
Россия, Tomsk; Tomsk
A. Chaikovskii
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: razinatg22@gmail.com
Россия, Tomsk
N. Isaikina
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: razinatg22@gmail.com
Россия, Tomsk
G. Kalinkina
Siberian State Medical University, Ministry of Health of the Russian Federation
Email: razinatg22@gmail.com
Россия, Tomsk
V. Zhdanov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine
Email: razinatg22@gmail.com
Россия, Tomsk
G. Zyuz’kov
E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine; National Research Tomsk State University
Email: razinatg22@gmail.com
Россия, Tomsk; Tomsk
Дополнительные файлы
