Isolation of primary osteoblast cell lines from adult rat and rat embryos and their use as models for in vitro biocompatibility tests of nanostructured titanium-based implants
- 作者: Vyalykh I.V.1, Korelin A.V.2, Belikov S.V.2, Karabanalov M.S.2, Rakitin S.B.3, Kamalov R.V.2, Popov A.A.2, Khrunyk Y.Y.2,3
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隶属关系:
- Ural Scientific Research Veterinary Institute
- Ural Federal University
- Institute of Plant and Animal Ecology, Ural Branch
- 期: 卷 475, 编号 1 (2017)
- 页面: 175-179
- 栏目: Cell Biology
- URL: https://journal-vniispk.ru/0012-4966/article/view/154128
- DOI: https://doi.org/10.1134/S0012496617040032
- ID: 154128
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详细
Methods for obtaining osteoblast cultures from the calvaria of adult Wistar rats and 12-day-old embryos of these rats have been adapted for studying the biocompatibility and ossointegration of titanium-based implants. The osteoblast morphology and their differentiation into osteocytes on a titanium matrix with specially treated surface have been studied. It has been confirmed that two cultures of diploid rat cells obtained in the study can serve as efficient models for preclinical in vitro testing of nanostructured titanium implants for biocompatibility and osseointegration.
作者简介
I. Vyalykh
Ural Scientific Research Veterinary Institute
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620000
A. Korelin
Ural Federal University
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620002
S. Belikov
Ural Federal University
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620002
M. Karabanalov
Ural Federal University
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620002
S. Rakitin
Institute of Plant and Animal Ecology, Ural Branch
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620144
R. Kamalov
Ural Federal University
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620002
A. Popov
Ural Federal University
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620002
Y. Khrunyk
Ural Federal University; Institute of Plant and Animal Ecology, Ural Branch
编辑信件的主要联系方式.
Email: juliakhrunyk@yahoo.co.uk
俄罗斯联邦, Yekaterinburg, 620002; Yekaterinburg, 620144
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