Effect of Ascorbic Acid Isomeric Forms on Antibacterial Activity of Its Chitosan Salts
Gegel’ N.O., Zudina I.V., Malinkina O.N., Shipovskaya A.B.
Abstract
Optical rotatory dispersion studies revealed water solutions of chitosan in L- and D-ascorbic acid to exhibit right rotation with anomalous dispersion and left rotation with normal dispersion, respectively. Microbiological investigation and transmission electron microscopy revealed the chitosan salt with D-ascorbic acid to cause deeper destructive changes than pure chitosan, which resulted in higher antibacterial activity against Staphylococcus aureus 209P and Escherichia coli 113-13.