The Common Partner of Several Methyltransferases Modifying the Components of The Eukaryotic Translation Apparatus


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Аннотация

TRM112 is necessary for the activation and stability of several methyltransferases involved in the modification of various components of the translation apparatus. This unique protein is a partner for enzymes that methylate tRNA, rRNA, and the translation termination factor. Here we review the structural and functional features of the TRM112 complexes with methyltransferases and provide, where possible, information on their significance.

Авторлар туралы

E. Vasilieva

Faculty of Bioengineering and Bioinformatics, Moscow State University

Хат алмасуға жауапты Автор.
Email: elnvasv@gmail.com
Ресей, Moscow, 119991

I. Laptev

Faculty of Chemistry, Moscow State University; Skolkovo Institute of Science and Technology

Email: elnvasv@gmail.com
Ресей, Moscow, 119991; Skolkovo, 143026

P. Sergiev

Faculty of Chemistry, Moscow State University; Skolkovo Institute of Science and Technology

Email: elnvasv@gmail.com
Ресей, Moscow, 119991; Skolkovo, 143026

O. Dontsova

Faculty of Chemistry, Moscow State University; Skolkovo Institute of Science and Technology; Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry

Email: elnvasv@gmail.com
Ресей, Moscow, 119991; Skolkovo, 143026; Moscow, 117997

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