Enviar artigo por via de e-mail Formulation Development and Study of Prolonged Release from Amben Peroral Preparations Based on Hydrophobic Matrices
- Autores: Nifontova G.O.1,2, Dolotova O.V.1, Sarantseva I.V.1, Akhmetzyanova A.R.3, Krechetov S.P.1, Krasnyuk I.I.2
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Afiliações:
- Life Sciences Center, Moscow Institute of Physics and Technology
- Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
- I. M. Sechenov First Moscow State Medical University
- Edição: Volume 50, Nº 2 (2016)
- Páginas: 90-95
- Seção: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journal-vniispk.ru/0091-150X/article/view/244325
- DOI: https://doi.org/10.1007/s11094-016-1404-3
- ID: 244325
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Resumo
Results from research on formulation development and prolonged release of peroral 4-aminomethylbenzoic acid (amben) using hydrophobic lipid and polymer matrices are reported. It is shown that the amben release parameters considering its solubility at various pH values can be achieved by using the studied polymer hydrophobic matrices.
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Sobre autores
G. Nifontova
Life Sciences Center, Moscow Institute of Physics and Technology; Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
Autor responsável pela correspondência
Email: galya.nif@yandex.ru
Rússia, Dolgoprudnyi, Moscow Oblast; Khimki, Moscow Oblast, 141402
O. Dolotova
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
Rússia, Dolgoprudnyi, Moscow Oblast
I. Sarantseva
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
Rússia, Dolgoprudnyi, Moscow Oblast
A. Akhmetzyanova
I. M. Sechenov First Moscow State Medical University
Email: galya.nif@yandex.ru
Rússia, Moscow, 119991
S. Krechetov
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
Rússia, Dolgoprudnyi, Moscow Oblast
I. Krasnyuk
Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
Email: galya.nif@yandex.ru
Rússia, Khimki, Moscow Oblast, 141402
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