Synthesis and Antiviral Activity of Hydroxy-Substituted Benzaldehydes and Related Compounds

O. I. Shadyro; V. L. Sorokin; G. A. Ksendzova; O. V. Savinova; S. N. Samovich; N. I. Pavlova; G. I. Polozov; E. I. Boreko

doi:10.1007/s11094-016-1414-1

Synthesis and Antiviral Activity of Hydroxy-Substituted Benzaldehydes and Related Compounds

Авторы: Shadyro O.I.¹, Sorokin V.L.¹, Ksendzova G.A.¹, Savinova O.V.¹, Samovich S.N.², Pavlova N.I.¹, Polozov G.I.¹, Boreko E.I.²
Учреждения:
1. Belarusian State University
2. State Research and Practical Center for Epidemiology and Microbiology
Выпуск: Том 50, № 3 (2016)
Страницы: 156-158
Раздел: Article
URL: https://journal-vniispk.ru/0091-150X/article/view/244335
DOI: https://doi.org/10.1007/s11094-016-1414-1
ID: 244335

Цитировать

Полный текст

Открытый доступ
Доступ закрыт

Доступ предоставлен
Доступ закрыт

Только для подписчиков

Аннотация
Об авторах
Список литературы
Дополнительные файлы
Статистика

Аннотация

A series of hydroxy-substituted benzaldehydes and related compounds were synthesized and studied in cell culture against herpes simplex type I (HSV-1) and influenza A (H7N1) viruses. It was found that salicylaldehyde, 2,3-dihydroxybenzaldehyde, and gossypol could suppress HSV-1 replication. The structure–activity relationship of the series of hydroxylated benzaldehydes was analyzed.