Отправить статью по E-mail Synthesis and Antiproliferative Activity of New Acylcatechins
- Авторы: Pozdeev A.O.1, Rasadkina E.N.1, Burym A.A.1, Knyazev V.V.2, Koroteev M.P.1, Matyushin A.I.2, Koroteev A.M.1, Semeikin A.V.2, Shimanovskii N.L.2
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Учреждения:
- Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
- Medical-Biology Department, Pirogov Russian National Research Medical University
- Выпуск: Том 50, № 8 (2016)
- Страницы: 523-525
- Раздел: Article
- URL: https://journal-vniispk.ru/0091-150X/article/view/244428
- DOI: https://doi.org/10.1007/s11094-016-1481-3
- ID: 244428
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Аннотация
New peracyl derivatives of the natural flavonoid (±)-catechin were synthesized. It was shown that carboxylic-acid acyl residues enhanced to various degrees the cytotoxicity of peracyl catechins against HeLa cell line. The structures of the synthesized compounds were confirmed by PMR and 13C NMR spectroscopy and elemental analysis. The catechins were compared with previously studied analogous dihydroquercetin derivatives.
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Об авторах
A. Pozdeev
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Автор, ответственный за переписку.
Email: Chemdept@mail.ru
Россия, 3 Nesvizhskii Per., Moscow, 119021
E. Rasadkina
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Россия, 3 Nesvizhskii Per., Moscow, 119021
A. Burym
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Россия, 3 Nesvizhskii Per., Moscow, 119021
V. Knyazev
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Россия, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
M. Koroteev
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Россия, 3 Nesvizhskii Per., Moscow, 119021
A. Matyushin
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Россия, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
A. Koroteev
Institute of Biology and Chemistry, Department of Organic Chemistry, Moscow State Pedagogical University
Email: Chemdept@mail.ru
Россия, 3 Nesvizhskii Per., Moscow, 119021
A. Semeikin
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Россия, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
N. Shimanovskii
Medical-Biology Department, Pirogov Russian National Research Medical University
Email: Chemdept@mail.ru
Россия, 9A/1 Bol’shaya Pirogovskaya St., Moscow, 119435
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