Отправить статью по E-mail Synthesis and Neurotropic Activity of New 7-Cyclohexyl-6,7,8,9-Tetrahydro-3H-Pyrazolo[3,4-c]-2,7-Naphthyridine-1,5-Diamines
- Авторы: Sirakanyan S.N.1, Hakobyan E.K.1, Nikoghosyan A.G.1, Paronikyan R.G.1, Dzhagatspanyan I.A.1, Nazaryan I.M.1, Akopyan A.G.1, Hovakimyan A.A.1
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Учреждения:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Выпуск: Том 52, № 2 (2018)
- Страницы: 108-111
- Раздел: Article
- URL: https://journal-vniispk.ru/0091-150X/article/view/245015
- DOI: https://doi.org/10.1007/s11094-018-1773-x
- ID: 245015
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Аннотация
A method for synthesizing new tricyclic heterocyclic 7-cyclohexyl-6,7,8,9-tetrahydro-3H-pyrazolo- [3,4-c]-2,7-naphthyridine-1,5-diamines from 1,3-dichloro-7-cyclohexyl-5,6, 7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile was elaborated. Investigation of the biological activity of the synthesized compounds showed that several of them exhibited pronounced neurotropic properties.
Об авторах
S. Sirakanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Автор, ответственный за переписку.
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
E. Hakobyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
A. Nikoghosyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
R. Paronikyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
I. Dzhagatspanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
I. Nazaryan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
A. Akopyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
A. Hovakimyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Армения, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
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