Bilateral lung lesion caused by benign metastasizing uterine myoma

Background: Benign metastasizing leiomyoma is a rare condition characterized by the development of multiple slow-growing tumors composed of smooth muscle cells that form in atypical locations, primarily in lung tissue. These tumors are usually discovered after a considerable period of time following a myomectomy. This pathology is characterized by a mostly asymptomatic course, which makes it difficult to detect and often leads to accidental detection during examinations for other reasons. Despite the benign histological picture, the tumor can have a clinically aggressive course and can result in serious complications as well as increase in mortality.

Case report: The article presents a clinical case of bilateral lung lesion caused by benign metastasizing leiomyoma in a 50-year-old woman after myomectomy performed 11 years before. The disease was characterized by the latent course; the pulmonary metastases were accidentally detected during a routine examination. The therapeutic strategy included consistent surgical resections of the lesions in combination with surgical hormonal deprivation.

Conclusion: Due to the lack of approved clinical protocols for managing patients with benign metastasizing leiomyoma, it is very important to have a systematic description of such cases, since it may give an insight into the pathophysiological mechanisms and characteristics of this disease. Each clinical observation has a significant scientific value and makes it possible to obtain the information for developing the optimal treatment approaches and evaluating prognostic criteria.