Innovative drugs: From basic research to production
- 作者: Myasoedov N.F.1
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隶属关系:
- Institute of Molecular Genetics
- 期: 卷 86, 编号 3 (2016)
- 页面: 151-157
- 栏目: Scientific Session of the General Meeting of the Russian Academy of Sciences
- URL: https://journal-vniispk.ru/1019-3316/article/view/178684
- DOI: https://doi.org/10.1134/S1019331616030084
- ID: 178684
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详细
The results of studies of the molecular action mechanism of the peptides Semax and Selank—simple glyprolines that are used to prepare peptide-based drugs—are presented. A concept of creating an amino acid sequence of peptides is given; their interaction with receptor systems of the cell and their influence on the cell’s transcriptome, which forms the cell-mediated response, are considered. On the basis of the findings, pharmaceutical compositions of peptide drugs have been developed and their production and introduction into clinical practice have been organized.
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