Differences in Nuclear Dynamics in Mouse GV Oocytes with a Diverse Chromatin Configuration

Аннотация

By means of time-lapse imaging, consistent patterns of nuclei movement in GV oocytes of SN and NSN types, differing in the chromatin configuration and the initial position of the nucleus, were established. Two types of movement specific for the GV oocyte nuclei were shown: directed motion from the periphery to the central region of the oocyte and oscillatory displacements in the central or peripheral region of the oocyte. It was noted that the nuclei of the NSN type oocytes with the initial position at the periphery hardly changed their position and oocytes died 3.5–4 h after the filming started.