Tris(2-hydroxyethyl)ammonium arylchalcogenylacetates, growth stimulants of alcohol yeast Saccharomyces cerevisiae

Abstract

A number of tris(2-hydroxyethyl)ammonium arylchalcogenylacetates ArYCH₂CO₂^–• •HN⁺(CH₂CH₂OH)₃ (1—4) (Ar = aryl; Y = O, S, SO₂) were synthesized. Their structure was established by IR and ¹H, ¹³C, ¹⁵N NMR spectroscopy. The influence of compounds 1—4 on the growth and development of yeast fungi Saccharomyces cerevisiae was studied. Compounds 1—4 were found to be efficient, safe, and available synthetic stimulants of these processes. The use of compounds 1—4 in low concentrations (from 10^–8 to 10^–4 wt.%, depending on the time of cultivation, concentration, and the anion type) reduced the lag-phases of development and increased the generation rate of yeast cells by 2—5 times. The amount of yeast cells increased by 2—3 times, while the content of protein in the biomass increased by 13—15%. The fermentation of sugar- and starch-containing raw material with yeast Saccharomyces cerevisiae increased the yield of ethyl alcohol (biofuel) by 5—9%.