Email this article Anion exchange kinetics with participation of cinchomeronic and dipicolinic acids
- Authors: Altshuler H.N.1, Shkurenko G.Y.1, Altshuler O.H.1,2
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Affiliations:
- Federal Research Center of Coal and Coal Chemistry, Siberian Branch of the Russian Academy of Sciences
- Kemerovo State University
- Issue: Vol 67, No 10 (2018)
- Pages: 1927-1930
- Section: Brief Communications
- URL: https://journal-vniispk.ru/1066-5285/article/view/243135
- DOI: https://doi.org/10.1007/s11172-018-2309-y
- ID: 243135
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Abstract
The rate of sorption and desorption of cinchomeronic and dipicolinic acids on the AB-17-8 strongly basic anion exchanger is limited by slow diffusion of components in the polymer phase. The diffusion coefficient of the organic anion in the phase of the AB-17-8 anion exchanger is equal to (3.7±0.5)•10–12 m2 s–1. Taking into account high rates of desorption of anions of cinchomeronic and dipicolinic acids from anionite (the half-transformation time is 6 min), the AB-17-8 strongly basic anion exchanger can be recommended for use as a container for development of prolonged drugs based on pyridinedicarboxylic acids.
About the authors
H. N. Altshuler
Federal Research Center of Coal and Coal Chemistry, Siberian Branch of the Russian Academy of Sciences
Author for correspondence.
Email: altshulerh@gmail.com
Russian Federation, 18 Sovetsky prosp., Kemerovo, 650000
G. Yu. Shkurenko
Federal Research Center of Coal and Coal Chemistry, Siberian Branch of the Russian Academy of Sciences
Email: altshulerh@gmail.com
Russian Federation, 18 Sovetsky prosp., Kemerovo, 650000
O. H. Altshuler
Federal Research Center of Coal and Coal Chemistry, Siberian Branch of the Russian Academy of Sciences; Kemerovo State University
Email: altshulerh@gmail.com
Russian Federation, 18 Sovetsky prosp., Kemerovo, 650000; 6 ul. Krasnaya, Kemerovo, 650043
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