电邮这篇文章 Effects of some 5-anilino-1,2,4-thiadiazole derivatives onto leukemic cells
- 作者: Orlova M.A.1,2, Trofimova T.P.1,2, Proshin A.N.3, Orlov A.P.1
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隶属关系:
- Department of Chemistry, M. V. Lomonosov Moscow State University
- Department of Biochemistry and Pharmacology, D. Rogachev Federal Clinical Center of Pediatric Hematology, Oncology and Immunology
- Department of Organic Synthesis, Institute of Physiological Active Compounds of Russian Academy of Sciences
- 期: 卷 66, 编号 5 (2017)
- 页面: 932-934
- 栏目: Brief Communications
- URL: https://journal-vniispk.ru/1066-5285/article/view/240654
- DOI: https://doi.org/10.1007/s11172-017-1833-5
- ID: 240654
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详细
The antileukemic activities of some thiadiazole derivatives in the forms of hydrochlorides and salicylates have been determined. The insertion of salicylate ion in the compound increases the therapeutic index, mainly due to the reduction of cytotoxicity against healthy cells.
作者简介
M. Orlova
Department of Chemistry, M. V. Lomonosov Moscow State University; Department of Biochemistry and Pharmacology, D. Rogachev Federal Clinical Center of Pediatric Hematology, Oncology and Immunology
编辑信件的主要联系方式.
Email: Orlova.radiochim@mail.ru
俄罗斯联邦, Bld. 3, 1 Leninskie Gory, Moscow, 119992; 1 ul. Samora Mashel, Moscow, 117997
T. Trofimova
Department of Chemistry, M. V. Lomonosov Moscow State University; Department of Biochemistry and Pharmacology, D. Rogachev Federal Clinical Center of Pediatric Hematology, Oncology and Immunology
Email: Orlova.radiochim@mail.ru
俄罗斯联邦, Bld. 3, 1 Leninskie Gory, Moscow, 119992; 1 ul. Samora Mashel, Moscow, 117997
A. Proshin
Department of Organic Synthesis, Institute of Physiological Active Compounds of Russian Academy of Sciences
Email: Orlova.radiochim@mail.ru
俄罗斯联邦, 1 Severnyi proezd, Chernogolovka, Moscow Region, 142432
A. Orlov
Department of Chemistry, M. V. Lomonosov Moscow State University
Email: Orlova.radiochim@mail.ru
俄罗斯联邦, Bld. 3, 1 Leninskie Gory, Moscow, 119992
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