Email this article N,N-Di(prop-2-yn-1-yl)adamantan-1-amines in 1,3-Dipolar Cycloaddition Reactions with Azide-Containing Pharmacophores
- Authors: Sokolov V.B.1, Aksinenko A.Y.1
-
Affiliations:
- Institute of Physiologically Active Substances of the Russian Academy of Sciences
- Issue: Vol 89, No 8 (2019)
- Pages: 1724-1727
- Section: Letters to the Editor
- URL: https://journal-vniispk.ru/1070-3632/article/view/223054
- DOI: https://doi.org/10.1134/S1070363219080280
- ID: 223054
Cite item
Open Access
Access granted
Subscription Access
Abstract
A synthetic approach to combining pharmacophore ligands with an aminoadamantyl-containing spacer based on a copper-catalyzed alkyne-azide 1,3-dipolar cycloaddition of N,N-di(prop-2-yne-1-yl)adamantan-1-amines and azido-containing carbazole, tetrahydrocarbazole, phenothiazine and adamantan-2-amine derivatives was proposed.
About the authors
V. B. Sokolov
Institute of Physiologically Active Substances of the Russian Academy of Sciences
Email: alaks@ipac.ac.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, 142432
A. Yu. Aksinenko
Institute of Physiologically Active Substances of the Russian Academy of Sciences
Author for correspondence.
Email: alaks@ipac.ac.ru
Russian Federation, Severnyi proezd 1, Chernogolovka, 142432
Supplementary files
