Synthesis and antibacterial activity of novel pyrano[2,3-d]pyrimidine-4-one–3-phenylisoxazole hybrids


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Resumo

A series of ethyl 2,7-dimethyl-4-oxo-5-phenyl-3-[(3-phenylisoxazol-5-yl)methyl]-3,5-dihydro-4H-pyrano[2,3-d]pyrimidine-6-carboxylates was synthesized and screened for antibacterial activity against Gram positive and Gram negative bacterial species. All new compounds were characterized by 1H, 13C NMR, IR, and mass spectra. The results of the antibacterial study indicated that all compounds exhibited good to excellent antibacterial activity.

Sobre autores

B. Kumar

Department of Chemistry, University College for Women

Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007

P. Lakshmi

Department of Chemistry, University College for Women

Autor responsável pela correspondência
Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007

B. Veena

Department of Botany, University College of Science

Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007

E. Sujatha

Department of Botany, University College of Science

Email: pvanantha.ou@gmail.com
Índia, Hyderabad, Telangana, 500007

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