Synthesis of 4-Aryl-2-hydroxy-4-oxo- N -{4-[(1,3-thiazol-2-yl)- sulfamoyl]phenyl}but-2-eneamides

V. L. Gein; O. V. Bobrovskaya; A. A. Russkikh; N. N. Petukhova

doi:10.1134/S1070363218020238

Synthesis of 4-Aryl-2-hydroxy-4-oxo-N-{4-[(1,3-thiazol-2-yl)- sulfamoyl]phenyl}but-2-eneamides

作者: Gein V.L.¹, Bobrovskaya O.V.¹, Russkikh A.A.¹, Petukhova N.N.¹
隶属关系:
1. Perm State Pharmaceutical Academy
期: 卷 88, 编号 2 (2018)
页面: 334-337
栏目: Letters to the Editor
URL: https://journal-vniispk.ru/1070-3632/article/view/222021
DOI: https://doi.org/10.1134/S1070363218020238
ID: 222021

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详细

The reaction of methyl aroylpyruvates with 2-(4-aminobenzenesulfamido)thiazole (norsulfazole) in glacial acetic acid in the presence of anhydrous sodium acetate furnished 4-aryl-2-hydroxy-4-oxo-N-{4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}but-2-eneamides.