Synthesis of sulfonamide derivatives of pyrido-[2,1- b ]quinazolin-11-one and pyrido[1,2- a ]quinazolin-6-one

R. M. Shlenev; S. I. Filimonov; A. V. Tarasov; A. S. Danilova; P. A. Agat’ev

doi:10.1134/S1070428016020147

Synthesis of sulfonamide derivatives of pyrido-[2,1-b]quinazolin-11-one and pyrido[1,2-a]quinazolin-6-one

Authors: Shlenev R.M.¹, Filimonov S.I.¹, Tarasov A.V.¹, Danilova A.S.¹, Agat’ev P.A.¹
Affiliations:
1. Yaroslavl State Technical University
Issue: Vol 52, No 2 (2016)
Pages: 240-243
Section: Article
URL: https://journal-vniispk.ru/1070-4280/article/view/213742
DOI: https://doi.org/10.1134/S1070428016020147
ID: 213742

Cite item

Full Text

Open Access
Restricted Access

Access granted
Restricted Access

Subscription Access

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

Methods were developed of indirect introduction of sulfonamide group in the structures of pyrido-[2,1-b]quinazolin-11-one and pyrido[1,2-a]quinazolin-6-one underlain by cyclocondensation of 2-halo-5-(Rsulfamoyl) benzoyl chlorides with derivatives of 2-aminopyridine. The fact of thermal rearrangement of 8-(morpholin-4-ylsulfonyl)pyrido[1,2-a]quinazolin-6-one into isomeric 2-(morpholine-4-ylsulfonyl)pyrido[2,1-b]-quinazolin-11-one was experimentally registered.