Practical F/Δ12,14-D transformation in the prostaglandin series. synthesis of methyl (±)-(5Z,12E,14E)-9α-acetoxy- 16-(3-chlorophenoxy)-15-deoxy-11-oxo-17,18,19,20-tetranorprosta- 5,12,14-trienoate from cloprostenol
- Авторлар: Vostrikov N.S.1, Lobko I.F.1, Spirikhin L.V.1, Miftakhov M.S.1
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Мекемелер:
- Ufa Institute of Chemistry
- Шығарылым: Том 52, № 12 (2016)
- Беттер: 1765-1772
- Бөлім: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/215424
- DOI: https://doi.org/10.1134/S1070428016120095
- ID: 215424
Дәйексөз келтіру
Аннотация
Methyl (±)-(5Z,12E,14E)-9α-acetoxy-16-(3-chlorophenoxy)-15-deoxy-11-oxo-17,18,19,20-tetranorprosta- 5,12,14-trienoate was synthesized via selective protection/deprotection of the hydroxy groups in cloprostenol methyl ester, followed by oxidation of the C11–OH group and DBU-promoted elimination of the 9-acetoxy group.
Авторлар туралы
N. Vostrikov
Ufa Institute of Chemistry
Email: bioreg@anrb.ru
Ресей, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
I. Lobko
Ufa Institute of Chemistry
Email: bioreg@anrb.ru
Ресей, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
L. Spirikhin
Ufa Institute of Chemistry
Email: bioreg@anrb.ru
Ресей, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
M. Miftakhov
Ufa Institute of Chemistry
Хат алмасуға жауапты Автор.
Email: bioreg@anrb.ru
Ресей, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
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