Tricomponent domino synthesis of 6-hydroxy-2-chloro-1,4,5,6-tetrahydropyridine-3,4,4-tricarbonitriles

O. V. Ershov; K. V. Lipin; A. V. Eremkin; O. E. Nasakin; V. P. Sheverdov; P. I. Fedorov; V. A. Tafeenko

doi:10.1134/S1070428017020129

Tricomponent domino synthesis of 6-hydroxy-2-chloro-1,4,5,6-tetrahydropyridine-3,4,4-tricarbonitriles

Authors: Ershov O.V.¹, Lipin K.V.¹, Eremkin A.V.¹, Nasakin O.E.¹, Sheverdov V.P.¹, Fedorov P.I.¹, Tafeenko V.A.²
Affiliations:
1. I.N. Ul’yanov Chuvash State University
2. Lomonosov Moscow State University
Issue: Vol 53, No 2 (2017)
Pages: 215-221
Section: Article
URL: https://journal-vniispk.ru/1070-4280/article/view/215757
DOI: https://doi.org/10.1134/S1070428017020129
ID: 215757

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Abstract

In reaction of tetracyanoethylene with ketones and HCl in 1,4-dioxane at 30–40°? 6-hydroxy-2-chloro-1,4,5,6-tetrahydropyridine-3,4,4-tricarbonitriles are formed.