Alkylation of 3-methyl-1H-acenaphtho[5,6-de]pyridazine


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Abstract

Alkylation of 3-methyl-1Н-acenaphtho[5,6]pyridazine with methyl and propyl iodides as well as with benzyl chloride in alkaline medium leads to the formation of the corresponding both N- and С-substituted pyridazine derivatives and also to the dimerization product of the initial compound. The ratio of obtained compounds depends on the used hydride, reaction temperature, and solvent.

About the authors

N. I. Omelichkin

Research Institute of Physical and Organic Chemistry at Southern Federal University

Author for correspondence.
Email: niomelichkin@sfedu.ru
Russian Federation, pr. Stachki 194/2, Rostov-on-Don, 344090

L. G. Minyaeva

Research Institute of Physical and Organic Chemistry at Southern Federal University

Email: niomelichkin@sfedu.ru
Russian Federation, pr. Stachki 194/2, Rostov-on-Don, 344090

V. V. Mezheritskii

Research Institute of Physical and Organic Chemistry at Southern Federal University

Email: niomelichkin@sfedu.ru
Russian Federation, pr. Stachki 194/2, Rostov-on-Don, 344090

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