Synthesis of ortho-carboranyl derivatives of (S)-asparagine and (S)-glutamine
- Authors: Gruzdev D.A.1, Levit G.L.1, Olshevskaya V.A.2, Krasnov V.P.1
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Affiliations:
- Postovsky Institute of Organic Synthesis, Ural Branch
- Nesmeyanov Institute of Organoelement Compounds
- Issue: Vol 53, No 5 (2017)
- Pages: 769-776
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/216258
- DOI: https://doi.org/10.1134/S1070428017050190
- ID: 216258
Cite item
Abstract
(S)-Asparagine and (S)-glutamine ortho-carboranyl derivatives with free amino and carboxy groups in the α-position were synthesized. By an example of Nγ-(1,2-dicarba-closo-dodecarboran-3-yl)-(S)-glutamine it was demonstrated that the developed synthetic approach carboranyl derivatives of amino acids allowed the preparation of optically pure isomers.
About the authors
D. A. Gruzdev
Postovsky Institute of Organic Synthesis, Ural Branch
Author for correspondence.
Email: gruzdev-da@ios.uran.ru
Russian Federation, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990
G. L. Levit
Postovsky Institute of Organic Synthesis, Ural Branch
Email: gruzdev-da@ios.uran.ru
Russian Federation, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990
V. A. Olshevskaya
Nesmeyanov Institute of Organoelement Compounds
Email: gruzdev-da@ios.uran.ru
Russian Federation, Moscow
V. P. Krasnov
Postovsky Institute of Organic Synthesis, Ural Branch
Email: gruzdev-da@ios.uran.ru
Russian Federation, ul. S. Kovalevskoi/Akademicheskaya 22/20, Yekaterinburg, 620990
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