Selective Formation of Products of Interrupted Feist-Benary Reaction under the Conditions of Hantzsch Pyrrole Synthesis

V. S. Matiichuk; D. A. Frolov; N. T. Pokhodylo; V. V. Pavlyuk; M. D. Obushak

doi:10.1134/S1070428018050238

Selective Formation of Products of Interrupted Feist-Benary Reaction under the Conditions of Hantzsch Pyrrole Synthesis

Authors: Matiichuk V.S.¹, Frolov D.A.¹, Pokhodylo N.T.¹, Pavlyuk V.V.¹, Obushak M.D.¹
Affiliations:
1. Ivan Franko Lviv National University
Issue: Vol 54, No 5 (2018)
Pages: 799-801
Section: Short Communications
URL: https://journal-vniispk.ru/1070-4280/article/view/217976
DOI: https://doi.org/10.1134/S1070428018050238
ID: 217976

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Abstract

Reaction of 3-aryl-2-chloropropanal with 1-arylsulfonylpropan-2-ones in aqueous ammonia and alcohol under the conditions of Hantzsch pyrrole synthesis led to the selective formation of the products of interrupted Feist-Benary reaction, 2-(R-benzyl)-4-arylsulfonyl-5-methyl-2,3-dihydrofuran-3-ols.