Synthesis and Chemical Transformations of 5-Alkyl(phenyl)-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-oles


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Abstract

5,5,7-Trimethyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol was synthesized by cyclocondensation of 3-amino-1,2,4-triazole with 4-methylpent-3-en-2-one; its chemical transformations, and also the transformations of 5-phenyl-4,5,6,7-tetrahydro[1,2,4]triazolo[1,5-a]pyrimidin-7-ol were investigated in reactions with reagents of diverse electronic nature.

About the authors

N. I. Zemlyanaya

Danilevsky Institute of Problems of Endocrine Pathology; Institute of Single Crystals

Email: lipson@ukr.net
Ukraine, ul. Alchevskikh 10, Kharkiv, 61002; Kharkiv, 61001

T. M. Karnozhitskaya

Danilevsky Institute of Problems of Endocrine Pathology

Email: lipson@ukr.net
Ukraine, ul. Alchevskikh 10, Kharkiv, 61002

V. I. Musatov

Institute of Single Crystals

Email: lipson@ukr.net
Ukraine, Kharkiv, 61001

I. S. Konovalova

Institute of Single Crystals

Email: lipson@ukr.net
Ukraine, Kharkiv, 61001

S. V. Shishkina

Institute of Single Crystals; Karazin Kharkiv National University

Email: lipson@ukr.net
Ukraine, Kharkiv, 61001; Kharkiv, 61022

V. V. Lipson

Danilevsky Institute of Problems of Endocrine Pathology; Institute of Single Crystals; Karazin Kharkiv National University

Author for correspondence.
Email: lipson@ukr.net
Ukraine, ul. Alchevskikh 10, Kharkiv, 61002; Kharkiv, 61001; Kharkiv, 61022

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