Synthetic Approaches to 15-Deoxy-Δ12,14-prostaglandin J2. A New Key Building Block Based on (3aR,6R,6aS)-6-Trimethylsilyl)-3,3a,6,6a-tetrahydro-1H-cyclopenta[c]furan-1-one
- Authors: Gimazetdinov A.M.1, Al’mukhametov A.Z.1, Miftakhov M.S.1
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Affiliations:
- Ufa Institute of Chemistry, Ufa Federal Research Center
- Issue: Vol 55, No 6 (2019)
- Pages: 831-836
- Section: Review
- URL: https://journal-vniispk.ru/1070-4280/article/view/220754
- DOI: https://doi.org/10.1134/S1070428019060137
- ID: 220754
Cite item
Abstract
{(1S,4R,5R)-5-[tert-Butyl(dimethyl)silyloxymethyl]-4-hydroxycyclopent-2-en-1-yl}acetaldehyde, the key building block in a possible approach to 15-deoxy-Δ12,14-prostaglandin J2, has been synthesized starting from (3aR,6R,6aS)-6-(trimethylsilyl)-3,3a,6,6a-tetrahydro-1H-cyclopenta[c]furan-1-one.
About the authors
A. M. Gimazetdinov
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: bioreg@anrb.ru
Russian Federation, Ufa, Bashkortostan
A. Z. Al’mukhametov
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: bioreg@anrb.ru
Russian Federation, Ufa, Bashkortostan
M. S. Miftakhov
Ufa Institute of Chemistry, Ufa Federal Research Center
Author for correspondence.
Email: bioreg@anrb.ru
Russian Federation, Ufa, Bashkortostan
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