Email this article Synthesis and Anticancer Activity of Certain Selenophene Derivatives
- Authors: Adly M.E.1, Gedawy E.M.1,2, El-Malah A.A.1,3, El-Telbany F.A.1
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Affiliations:
- Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy
- Pharmaceutical Chemistry Department, Faculty of Pharmacy and Pharmaceutical Industries
- Pharmaceutical Chemistry Department, Faculty of Pharmacy and Drug Technology
- Issue: Vol 55, No 8 (2019)
- Pages: 1189-1196
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/221076
- DOI: https://doi.org/10.1134/S1070428019080189
- ID: 221076
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Abstract
Selenopheno[2,3-d]pyrimidine- and selenopheno[2,3-d][1,2,3]triazine-containing compounds were synthesized starting from 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]selenophene-3-carbonitrile. In vitro anticancer activity of the newly synthesized compounds was tested using 60 different human cancer cell lines.
About the authors
M. E. Adly
Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy
Author for correspondence.
Email: mina.magharyos@pharma.cu.edu.eg
Egypt, Cairo, 11562
E. M. Gedawy
Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy; Pharmaceutical Chemistry Department, Faculty of Pharmacy and Pharmaceutical Industries
Email: mina.magharyos@pharma.cu.edu.eg
Egypt, Cairo, 11562; Cairo, 11829
A. A. El-Malah
Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy; Pharmaceutical Chemistry Department, Faculty of Pharmacy and Drug Technology
Email: mina.magharyos@pharma.cu.edu.eg
Egypt, Cairo, 11562; Cairo, 11785
F. A. El-Telbany
Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy
Email: mina.magharyos@pharma.cu.edu.eg
Egypt, Cairo, 11562
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