Green Regioselective Synthesis of (Purin-6-yl)hydrazones
- Authors: Kapadiya K.M.1, Dhalani J.M.1, Patel B.Y.2
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Affiliations:
- School of Science, Department of Chemistry, Bio-Research and Characterization Laboratory
- B.V. Shah (Vadivihar) Science College, Department of Chemistry
- Issue: Vol 55, No 10 (2019)
- Pages: 1575-1579
- Section: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/221284
- DOI: https://doi.org/10.1134/S1070428019100178
- ID: 221284
Cite item
Abstract
Some unique purine hydrazinylidene derivatives were synthesized by the regioselective reaction of 2,6-dichloropurine with hydrazine hydrate, followed by condensation with commercially available 1,3-dicarbonyl compounds according to a green chemistry approach. The structures of the synthesized compounds were confirmed by 1H and 13C NMR, IR, and mass spectra and elemental analyses. The regioselectivity of chlorine substitution in 2,6-dichloropurine was established by HMBC (Heteronuclear Multiple Bond Correlation) NMR technique.
About the authors
K. M. Kapadiya
School of Science, Department of Chemistry, Bio-Research and Characterization Laboratory
Author for correspondence.
Email: khushal_kapadiya06@yahoo.com
India, Rajkot, Gujarat
J. M. Dhalani
School of Science, Department of Chemistry, Bio-Research and Characterization Laboratory
Email: khushal_kapadiya06@yahoo.com
India, Rajkot, Gujarat
B. Y. Patel
B.V. Shah (Vadivihar) Science College, Department of Chemistry
Email: khushal_kapadiya06@yahoo.com
India, Wadhwancity, Surendranagar, Gujarat
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