Efficient Microwave-Assisted Synthesis of Some N-Heterocycles Integrated with a Pyrazole Moiety


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Abstract

An efficient and rapid synthesis of new heterocyclic compounds via reactions of 1,3-diphenyl-1H-pyrazole-4-carbaldehyde thiosemicarbazone with some carbon electrophiles, namely dimethyl acetylenedicar-boxylate, maleic anhydride, and ω-bromoacetophenone, under microwave irradiation has been developed. The structure of the synthesized compounds was confirmed by their analytical and spectral data.

About the authors

S. K. Ramadan

Chemistry Department, Faculty of Science

Author for correspondence.
Email: sayed.karam2008@sci.asu.edu.eg
Egypt, Abbassia, Cairo

E. A. E. El-Helw

Chemistry Department, Faculty of Science

Email: sayed.karam2008@sci.asu.edu.eg
Egypt, Abbassia, Cairo

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