Synthesis of functional isoxazole and isothiazole derivatives from [(5-arylisoxazol-3-yl)methoxy]arylmethanols

Аннотация

A procedure has been developed for the synthesis of functional isoxazole and isothiazole derivatives by reduction of (5-aryl-1,2-oxazol-3-yl)methoxybenzaldehydes to (5-aryl-1,2-oxazol-3-yl)methoxyaryl-methanols and subsequent acylation of the latter with isoxazole- and isothiazolecarbonyl chlorides.