Synthesis of 1-[4-(1,3-diaryl-4,5-dihydro-1H-pyrazol-5-yl)-2,3,5,6-tetrafluorophenyl]piperidin-4-ols and their acrylates

Аннотация

(4-Hydroxypiperidin-1-yl)tetra- and -octafluorochalcones reacted with phenylhydrazine in acetic acid to give mixtures of polyfluoro-1,3,5-triaryl-4,5-dihydro-1H-pyrazoles and their O-acetyl derivatives. Analogous reactions in ethanol afforded in satisfactory yields 1-[4-(1,3-diaryl-4,5-dihydro-1H-pyrazol-5-yl)-2,3,5,6-tetrafluorophenyl]piperidin-4-ols which were treated with acryloyl chloride to obtain the corresponding acrylates that are promising as monomers for the preparation of fluorescent films.