Enviar artigo por via de e-mail Synthesis of an Acyclic Precursor to Epothilone D Analog. Aldol Condensation of (1R)-1-(1,3-Dithiolan-2-yl)-1-(methoxymethoxy)- 2,2-dimethylpentan-3-one with C6‒C21 and C6‒C9 Aldehyde Segments
- Autores: Valeev R.F.1, Sunagatullina G.R.1, Loza V.V.1, Miftakhov M.S.1
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Afiliações:
- Ufa Institute of Chemistry, Ufa Federal Research Center
- Edição: Volume 54, Nº 10 (2018)
- Páginas: 1548-1552
- Seção: Article
- URL: https://journal-vniispk.ru/1070-4280/article/view/219284
- DOI: https://doi.org/10.1134/S1070428018100172
- ID: 219284
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Resumo
The synthesis of acyclic precursors to epothilone D analogs has been explored. Optimal conditions have been found for enolization of (1R)-1-(1,3-dithiolan-2-yl)-1-(methoxymethoxy)-2,2-dimethylpentan-3-one and its aldol condensation with C6‒C21 and C6‒C9 aldehydes.
Sobre autores
R. Valeev
Ufa Institute of Chemistry, Ufa Federal Research Center
Autor responsável pela correspondência
Email: rusl0@yandex.ru
Rússia, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
G. Sunagatullina
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: rusl0@yandex.ru
Rússia, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
V. Loza
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: rusl0@yandex.ru
Rússia, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
M. Miftakhov
Ufa Institute of Chemistry, Ufa Federal Research Center
Email: rusl0@yandex.ru
Rússia, pr. Oktyabrya 71, Ufa, Bashkortostan, 450054
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