Synthesis and some chemical characteristics of 4″-nitro-3,3′:4′,3″-ter-1,2,5-oxadiazol-4-amine

详细

A convenient preparation method was developed for 4″-nitro-3,3′:4′,3″-ter-1,2,5-oxadiazol-4-amine by substituting one nitro group of 4,4″-dinitro-3,3′:4′,3″-ter-1,2,5-oxadiazole at treating with equivalent quantity of ammonia in solvents of low polarity. In the reaction of the obtained amino-nitro derivative with N- and О- nucleophiles depending on the reaction conditions and the nucleophile nature either substitution of the nitro group occurs for the nucleophile residue to form 4″-alkoxy-, azido-, hydraznyl- or mono- and dialkylamino-[3,3′;4′,3″]-ter(1,2,5-oxadiazol)-4-ylamines, or the compound suffers an intramolecular cyclization affording 7Н-tri-1,2,5-oxadiazolo[3,4-b:3′,4′-d:3″,4″-f]azepines.