Synthesis of New Derivatives of 4-(1,4-Benzodioxan-2-yl)thiophene

S. O. Vardanyan; A. A. Aghekyan; A. S. Avagyan; S. A. Harutyunyan; H. V. Gasparyan

doi:10.1134/S1070428019050038

Synthesis of New Derivatives of 4-(1,4-Benzodioxan-2-yl)thiophene

作者: Vardanyan S.O.¹, Aghekyan A.A.¹, Avagyan A.S.¹, Harutyunyan S.A.¹, Gasparyan H.V.¹
隶属关系:
1. Scientific Technological Centre of Organic and Pharmaceutical Chemistry
期: 卷 55, 编号 5 (2019)
页面: 598-601
栏目: Article
URL: https://journal-vniispk.ru/1070-4280/article/view/220487
DOI: https://doi.org/10.1134/S1070428019050038
ID: 220487

如何引用文章

全文:

开放存取

##reader.subscriptionAccessGranted##
受限制的访问

订阅存取

详细
作者简介
参考
补充文件
统计

详细

thyl 2-amino-4-(1,4-benzodioxan-2-yl)thiophene-3-carboxylate was synthesized by the Gewald reaction of 2-acetyl-1,4-benzodioxane with ethyl 2-cyanoacetate and sulfur in the presence of diethylamine. The product was used to synthesize a series of amido ester derivatives with various pharmacophoric fragments. The antihypoxic properties of the synthesized amido esters were investigated.