Ring Opening of 4-Arylamino-2-tert-butyl-5-oxo-2,5-dihydrofuran-2-yl Acetates with Aromatic and Heterocyclic Amines


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Reactions of 4-arylamino-2-tert-butyl-5-oxo-2,5-dihydrofuran-2-yl acetates with an equimolar amount of aromatic or heterocyclic amine in toluene involves initial attack of the amine on the C2 atom of the furan ring, followed by opening of the furan ring and elimination of acetic acid to give N-aryl(hetaryl)-2-arylamino-5,5-dimethyl-4-oxohex-2-enamides.

作者简介

N. Igidov

Perm State Pharmaceutical Academy

Email: rubtsov@psu.ru
俄罗斯联邦, Perm

A. Rubtsov

Perm State National Research University

编辑信件的主要联系方式.
Email: rubtsov@psu.ru
俄罗斯联邦, Perm

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