Far North residents’ age-related peculiarities based on construction of functional state matrices

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Abstract

BACKGROUND: Living in Russia’s Far North contributes to pronounced natural and social characteristics that exert an unfavorable influence on the human functional state.

AIM: This study assessed medical, physiological, and social factors determining the body functional state in northerners of different age groups.

METHODS: The research involved male residents of Magadan region, Caucasians by origin: 156 young men aged 17–21 (18.5±0.6) years, 56 men of the working age of 34–45 (37.4±0.5) years, and 45 elderly men aged 60–77 (65.9±1.1) years. The participants’ somatometric variables were measured. The functioning of cardiovascular and respiratory systems, insulin resistance, as well as the levels of blood biochemistry, vitamin D, trace element, and basal metabolism were assessed. The subjective tobacco smoking and motor activity rates were also analyzed.

RESULTS: We can conclude that the body systemic functioning is increasingly stressed out with age. The sampled people exhibited higher incidence of arterial hypertension, which was rated in total by subjective systolic and diastolic blood pressure, with the incidence growing with increasing age, from 49% in younger subjects to 108% in older men; more common insulin resistance, from 13% in the youth to 50% in the elderly; elevated blood glucose level which was ranging (29%, 30%, 43% with age, respectively); and deviation of the atherogenicity coefficient rising from 9% to 55%–60% with increasing age. We also observed the same dependence of bronchial obstruction variables on age: from 19% incidence among younger subjects to 71% and 74% in middle-aged and older men, respectfully, with impaired respiratory functioning and consistently high levels (40%–59%) of reported tobacco consumption.

CONCLUSION: The developed matrices illustrate the worsening observed in subjective functional reserves and increasing intensity occurred in body systems of examinees as they grow from ontogenesis of the youth to the elderly.

About the authors

Inessa V. Averyanova

Scientific Research Center “Arktika” (SRC “Arktika” FEB RAS)

Email: Inessa1382@mail.ru
ORCID iD: 0000-0002-4511-6782
SPIN-code: 9402-0363
Scopus Author ID: 57009034300
ResearcherId: 9371-2020

MD, Dr. Sci. (Biol.), leader research associate

Russian Federation, Magadan

Elena A. Lugovaya

Scientific Research Center “Arktika” (SRC “Arktika” FEB RAS)

Email: elena_plant@mail.ru
ORCID iD: 0000-0002-6583-4175
SPIN-code: 5825-7122
Scopus Author ID: 56728609500
ResearcherId: AAR-7391-2020
Russian Federation, Magadan

Sergei I. Vdovenko

Scientific Research Center “Arktika” (SRC “Arktika” FEB RAS)

Email: vdovenko.sergei@yandex.ru
ORCID iD: 0000-0003-4761-5144
SPIN-code: 5475-4644
Scopus Author ID: 55253079000
ResearcherId: AAZ-5400-2020
Russian Federation, Magadan

Yuriy V. Barbaruk

Scientific Research Center “Arktika” (SRC “Arktika” FEB RAS)

Author for correspondence.
Email: barbaruk@mail.ru
ORCID iD: 0000-0003-3429-7685
SPIN-code: 5574-4008
Scopus Author ID: 5721557633
ResearcherId: H-8971-2016
Russian Federation, Magadan

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2. Fig. 1. Matrices for the decline of functional reserves in the ontogenetic aspect: 1 — proportion of persons with body mass index more than 25 kg/m2; 2 — proportion of persons with high normal blood pressure and arterial hypertension in total by BPS (mmHg) and BPD (mmHg); 3 — mean variable of patency of large bronchi below the proper value; 4 — mean variable of patency of medium bronchi below the proper value; 5 — mean variable of patency of small bronchi below the proper value; 6 — proportion of persons with the Gensler Index below the standard range (85 conv. units); 7 — resting energy expenditure per day (REE, kcal per day) above the proper value; 8 — proportion of persons with the coefficient of atherogenicity of the lipid spectrum above the standard range; 9 — proportion of persons with the blood glucose level above 5.6 mmol/L; 10 — proportion of persons with HOMA-IR (insulin resistance index) above 2.7 conv. units; 11 — proportion of persons with vitamin D deficit and insufficiency; 12 — proportion of persons with vitamin B12 deficit and insufficiency; 13 — total percentage of the deficit trace element incidence /10; 14 — total percentage of the excess trace element incidence /10; 15 — proportion of persons with an addiction to tobacco smoking; 16 — proportion of persons with a reduced motor activity and hypodynamia. Dimensionality of axes is from 0 to 110%.

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