B.G. Yudin's activities in the problem fields of bioethics research have been stimulating discussions among representatives of various sciences, doctors, lawyers, politicians, and clergymen. His scientific ideas about the principles, rules, and problems of bioethics are historically closely connected with the views of outstanding representatives of Russian medicine. They resonate with the ethical principles of his domestic contemporaries, and they are the basis for studying the creative heritage of those healers. This article analyzed the ethical principles of V.F. Voyno-Yasenetsky, an outstanding national humanist, scientist, surgeon, archbishop, whose work focused on a number of bioethical problems arising in the fields of transplantology, oncology, surgery, gynecology, ophthalmology, doctor-patient relationships, and doctor-paramedical personnel interaction. The influence of his religious views on the problems of bioethics was also analyzed.. The ethical principles of V.F. Voyno-Yasenetsky developed in the difficult conditions of tragic political events, repressions, during the Great Patriotic War. During this period V.F. Voyno-Yasenetsky was actively involved in practical medical and scientific work, at the same time performing the activities of the clergyman. One of the problems of modern domestic medicine is that it develops as a multibranch system, seemingly aimed to study humans, but it tends to ignore the personality of the patient as an individual identity due to progressing schematism of thinking. It seems to be a sign of a decreased value of the art of healing. The solution of the problem requires a philosophical reflection in the value and purpose, procedural, outcome contexts. A convincing example of such a solution is the activity and creative work of the outstanding domestic surgeon, the archbishop V.F. Voyno-Yasenetsky, whose ethical principles are based on the philosophy of personal education and determined the scope and efficacy of his activities: medical, scientific, educational, administrative and organizational fields.