Rare co-occurrence of multiple sclerosis and Parkinson's disease: a case report
- 作者: Ruina E.A.1, Aleksandrova E.A.2, Parshina E.V.3, Rodygin D.N.2, Yulin V.S.2
-
隶属关系:
- Volga Research Medical University
- Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashko
- Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashk
- 期: 卷 16, 编号 3 (2022)
- 页面: 83-91
- 栏目: Clinical analysis
- URL: https://journal-vniispk.ru/2075-5473/article/view/124069
- DOI: https://doi.org/10.54101/ACEN.2022.3.10
- ID: 124069
如何引用文章
全文:
详细
A review of Russian and foreign medical literature, as well as the Web of Science, PubMed and Scopus databases, revealed 8 cases of multiple sclerosis and Parkinson's disease co-occurrence. Parkinson's disease is a chronic, progressive neurological disease caused by degeneration of dopaminergic neurons in the substantia nigra. Multiple sclerosis is a chronic demyelinating disease, in which a range of autoimmune-driven inflammatory and neurodegenerative processes lead to formation of numerous focal and diffuse lesions in the central nervous system, resulting in disability and a significant decrease in patient quality of life. The co-occurrence of these two neurodegenerative CNS disorders is rarely seen in clinical practice.
The authors describe a clinical case to demonstrate their approach to the diagnosis and management of this patient group.
作者简介
Ekaterina Ruina
Volga Research Medical University
Email: vadik.yulin@yandex.ru
ORCID iD: 0000-0003-4595-2614
Cand. Sci. (Med.), Associate Professor, Department of neurology, psychiatry and narcology
俄罗斯联邦, Nizhny NovgorodEkaterina Aleksandrova
Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashko
Email: vadik.yulin@yandex.ru
ORCID iD: 0000-0001-5012-945X
Cand. Sci. (Med.), Associate Professor, neurologist, Cabinet of extrapyramidal disorders
俄罗斯联邦, Nizhny NovgorodElena Parshina
Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashk
Email: vadik.yulin@yandex.ru
ORCID iD: 0000-0001-7033-053X
Cand. Sci. (Med.), Head, Neurological department
俄罗斯联邦, Nizhny NovgorodDanil Rodygin
Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashko
Email: vadik.yulin@yandex.ru
ORCID iD: 0000-0002-3191-4249
neurologist, Neurological department
俄罗斯联邦, Nizhny NovgorodVadim Yulin
Nizhny Novgorod Regional Clinical Hospital named after N.A. Semashko
编辑信件的主要联系方式.
Email: vadik.yulin@yandex.ru
ORCID iD: 0000-0003-3956-2986
neurologist, Neurological department
俄罗斯联邦, Nizhny Novgorod参考
- Friese M.A., Schattling B., Fugger L. Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis. Nat. Rev. Neurol. 2014; 10(4): 225–238. doi: 10.1038/nrneurol.2014.37
- Correale J., Marrodan M., Ysrraelit M.C. Mechanisms of neurodegeneration and axonal dysfunction in progressive multiple sclerosis. Biomedicines. 2019; 7(1): 14. doi: 10.3390/biomedicines7010014
- Höftberger R., Lassmann H. Inflammatory demyelinating diseases of the central nervous system. Handb. Clin. Neurol. 2017; 145: 263–283. doi: 10.1016/B978-0-12-802395-2.00019-5
- Иллариошкин С.Н., Яхно Н.Н. Болезнь Паркинсона и расстройства движения. М.; 2008. 405 с. Illarioshkin S.N., Yakhno N.N. Parkinson’s disease and movement disorders. Moscow; 2008. 405 p. (In Russ.)
- Mochizuki A., Komatsuzaki Y., Shoji S. Association of Lewy bodies and glial cytoplasmic inclusions in the brain of Parkinson’s disease. Acta Neuropathol. 2002; 104(5): 534–537. doi: 10.1007/s00401-002-0582-0
- Dugger B.N., Dickson D.W. Pathology of neurodegenerative diseases. Cold Spring Harb. Perspect. Biol. 2017; 9(7): a028035. doi: 10.1101/cshperspect.a028035
- Klingelhoefer L., Reichmann H. Pathogenesis of Parkinson disease — the gut-brain axis and enviromental factors. Nat. Rev. Neurol. 2015; 11(11): 625–636. doi: 10.1038/nrneurol.2015.197
- Иллариошкин С.Н., Левин О.С. Руководство по диагностике и лечению болезни Паркинсона. М.; 2017. 336 с. Illarioshkin S.N., Levin O.S. Guide to diagnosis and treatment of Parkinson’s disease. Moscow; 2017. 336 p. (In Russ.)
- Delalić S., Rus T., Ledinek A. et al. Parkinson’s disease in a patient with multiple sclerosis and heterozygous glucocerebrosidase gene mutation. Clin. Parkinson. Relat. Dis. 2020; 3: 100055. doi: 10.1016/j.prdoa.2020.100055
- Etemadifar M., Afshar F., Nasr Z., Kheradmand M. Parkinsonism associated with multiple sclerosis: a report of eight new cases and a review on the literature. Iran J. Neurol. 2014; 13(2): 88–93.
- Jellinger K.A. Multiple system atrophy: an oligodendroglioneural synuclei- nopathy. J. Alzheimers Dis. 2018; 62(3): 1141–1179. doi: 10.3233/JAD-170397
- Li X., Sundquist J., Sundquist K. Subsequent risks of Parkinson disease in patients with autoimmune and related disorders: a nationwide epidemiological study from Sweden. Neurodegener. Dis. 2012; 10: 277–284. doi: 10.1159/000333222
- Rugbjerg K., Friis S., Ritz B. et al. Autoimmune disease and risk for Parkinson disease: a population-based case-control study. Neurology. 2009; 73(18): 1462–1468. doi: 10.1212/WNL.0b013e3181c06635
- Sawcer S. The complex genetic of multiple sclerosis: pitfalls and prospects. Brain. 2008; 131(Pt 12): 3118–3131. doi: 10.1093/brain/awn081
- Иллариошкин С.Н. Ершова М.В., Ахмадуллина Д.Р., Федотова Е.Ю., Cовременные представления о мультисистемной атрофии. Нервные болезни. 2018; (4): 3–13. Illarioskin S.N., Ershova M.V., Ahmadullina D.R., Fedotova E.Yu. Current concept of multiple system atrophy. Nervnyye bolezni. 2018; (4): 3–13. (In Russ.)
- Compston A., Coles A. Multiple sclerosis. Lancet. 2002; 359: 1221–1231. doi: 10.1016/S0140-6736(02)08220-X
补充文件
