INDICES OF IMMUNE RESPONSE IN PATIENTS OF FALCIPARUM MALARIA IN REPUBLIC OF GUINEA
- 作者: Boiro M.Y.1, Boumbali S.1, Konstantinov O.K.1, Kalivogui S.1, Koulibali M.2, Bah A.S.1
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隶属关系:
- Pasteur Institute of Guinea
- International Research Center of Tropical Infections
- 期: 卷 6, 编号 2 (2016)
- 页面: 151-156
- 栏目: ORIGINAL ARTICLES
- URL: https://journal-vniispk.ru/2220-7619/article/view/118480
- DOI: https://doi.org/10.15789/2220-7619-2016-2-151-156
- ID: 118480
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Malaria in the Republic of Guinea is the main cause of morbidity and lethality. It takes the first place in number of all visits in medical service (30–40%) and is the main cause of hospital death. One records annually more than 8 millions malaria cases, and about 60 000 children deaths. Results of study of immune response changing on different disease phases in treatment of autochthon population and immune status of Europeans are presented. It was shown that immunity status (cellular and humoral) in population of Guinea (an endemic country on falciparum malaria) differs from one in Europeans living in tropics. During light forms of malaria one records an increase of T-lymphocyte and IgG number, whereas in grave cases one observed the acute decrease of these indices. The essential increase of B-lymphocyte number does not depends from gravity of disease and from malaria treatment. It was established that appearance of LSA1-41 antibodies was in a more degree in adult patients than in children. The positive correlation between IgM and IgG was established in adult patients as in children.
作者简介
M. Boiro
Pasteur Institute of Guinea
Email: fake@neicon.ru
PhD (Biology), Professor, General Director,
Kindia
几内亚S. Boumbali
Pasteur Institute of Guinea
Email: fake@neicon.ru
PhD (Biology), Professor, Director of Doctor’s School,
Kindia
几内亚O. Konstantinov
Pasteur Institute of Guinea
编辑信件的主要联系方式.
Email: olegkonst@mail.ru
PhD (Biology), Researcher,
Kindia, ВР146
几内亚S. Kalivogui
Pasteur Institute of Guinea
Email: fake@neicon.ru
PhD (Biology), Vice-Director,
Kindia
几内亚M. Koulibali
International Research Center of Tropical Infections
Email: fake@neicon.ru
PhD (Biology), Director,
Nzerekore
几内亚A. Bah
Pasteur Institute of Guinea
Email: fake@neicon.ru
Researcher,
Kindia
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