Features of acute purulent lymphadenites and maxillofacial adenophlegmons course in children

Objective. The purpose of the research was to study the features of the course of acute purulent lymphadenites and adenophlegmons of the maxillofacial region in children, to describe the species composition of pathogens, to determine their sensitivity to antibiotics of various groups.

Materials and methods. The medical histories of 147 patients were analyzed; microbiological studies were carried out (microscopic examination of clinical specimens with gram stain, cultural method, determination of sensitivity of isolated pathogen to antimicrobial drugs).

Results. Most often, acute purulent lymphadenites and adenophlegmons were observed in the submandibular tissue space (40.1 %) and in the neck (38.1 %). The main causative agents of the inflammatory process were Staphylococcus aureus (38.1 %) and Streptococcus agalactiae (BHSA) (14.3 %). Staphylococcus aureus strains had the highest sensitivity to beta-lactam antibiotics – in 83 %, to macrolides – in 60.4 %, to fluoroquinolones – in 56.6 %; 3.8 % showed resistance to lincomycin, 1.9 % – to beta-lactams. The strains of Streptococcus agalactiae (BHSA) were 100 % sensitive to beta-lactams, 73.7 % – to macrolides, they were resistant to lincomycin and macrolides (10.5 % each).

Conclusions. The data obtained are of great practical importance, since they allow to correctly orient doctors in the choice of rational antibiotic therapy.