The preoperative assessment of the stroke risk in oncosurgery
- 作者: Tsygan N.V.1,2, Yakovleva V.A.1,3, Fufaev E.E.1, Ismail R. Eleskhanov I.R.4, Sapozhnikov K.V.1, Nechiporuk V.M.1, Ilya I. Dzidzava I.I.1, Litvinenko I.V.5
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隶属关系:
- Military Medical Academy
- B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Centre "Kurchatov Institute"
- Raisa Gorbacheva Memorial Institute for Children Hematology and Transplantation
- 1477 Naval Clinical Hospital of the Pacific Fleet, Branch № 2
- Военно-медицинская академия
- 期: 卷 41, 编号 4 (2022)
- 页面: 365-370
- 栏目: Original articles
- URL: https://journal-vniispk.ru/RMMArep/article/view/111863
- DOI: https://doi.org/10.17816/rmmar111863
- ID: 111863
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AIM: of the research was to develop a mathematical model for the preoperative assessing of the stroke risk in surgical operations for malignant neoplasms of the chest and abdomen for the early identification of high-risk patients optimization of diagnostics and enhancing the efficacy of personalized preventive measures.
MATERIALS AND METHODS: 47 cases of perioperative stroke according to archived case histories patients with malignant neoplasms of various localization — retrospective analysis anamnesis of life and underlying disease, analysis of clinical and laboratory examination data, analysis of parameters associated with surgery and anesthetic aid, analysis of the clinical and neuroimaging picture of perioperative stroke; 102 patients who underwent elective surgery for the malignant neoplasm of the chest or abdomen — perioperative dynamic neurological support collection of anamnesis of life and disease, analysis of clinical and laboratory examination data, neurological examination with NIHSS and mRankin scores, neuropsychological testing using MoCA and FAB.
RESULTS: Risk factors for perioperative stroke in oncosurgical patients, as well as cerebroprotective factors have been established. The valid mathematical model was developed for assessing of the likelihood of perioperative stroke in the surgical treatment of malignant neoplasms of the chest and abdomen with a predictive power of 85.4%, sensitivity of 77%, and specificity of 87%.
CONCLUSION: The proposed mathematical model allows preoperatively assess the risk of perioperative stroke in percentage (according to the anamnesis and medical records data) and identify the group of high-risk patients.
作者简介
Nikolay Tsygan
Military Medical Academy; B.P. Konstantinov Petersburg Nuclear Physics Institute, National Research Centre "Kurchatov Institute"
Email: 1860n@mail.ru
ORCID iD: 0000-0002-5881-2242
SPIN 代码: 1006-2845
Scopus 作者 ID: 37066611200
Researcher ID: H-9132-2016
M.D., D.Sc. (Medicine), Associate Professor
俄罗斯联邦, Saint Petersburg; Gatchina, Leningrad regionVictoria Yakovleva
Military Medical Academy; Raisa Gorbacheva Memorial Institute for Children Hematology and Transplantation
Email: 24ro80@gmail.com
ORCID iD: 0000-0002-9839-3169
SPIN 代码: 6158-5505
Scopus 作者 ID: 56941569100
Researcher ID: AAZ-6393-2021
俄罗斯联邦, Saint Petersburg; Saint Petersburg
Evgeniy Fufaev
Military Medical Academy
Email: Fufaev.jj@gmail.com
SPIN 代码: 5758-2364
M.D., Ph.D. (Medicine), Associate Professor
俄罗斯联邦, Saint PetersburgIsmail Ismail R. Eleskhanov
1477 Naval Clinical Hospital of the Pacific Fleet, Branch № 2
Email: eleshanov_ir@mail.ru
SPIN 代码: 7413-6348
俄罗斯联邦, Petropavlovsk-Kamchatsky
Kirill Sapozhnikov
Military Medical Academy
Email: marinheira@rambler.ru
ORCID iD: 0000-0002-2476-7666
SPIN 代码: 2707-0339
Scopus 作者 ID: 57200810332
Researcher ID: ААЕ-3453-2022
俄罗斯联邦, Saint Petersburg
Vasilii Nechiporuk
Military Medical Academy
Email: me1225@bk.ru
SPIN 代码: 2437-4331
俄罗斯联邦, Saint Petersburg
Ilya Ilya I. Dzidzava
Military Medical Academy
Email: dzidzava@mail.ru
ORCID iD: 0000-0002-5860-3053
SPIN 代码: 7336-9643
Scopus 作者 ID: 8901380100
Researcher ID: Q-1992-2016
M.D., D.Sc. (Medicine), Associate Professor
俄罗斯联邦, Saint PetersburgIgor Litvinenko
Военно-медицинская академия
编辑信件的主要联系方式.
Email: litvinenkoiv@rambler.ru
ORCID iD: 0000-0001-8988-3011
SPIN 代码: 6112-2792
Scopus 作者 ID: 35734354000
Researcher ID: F-9120-2013
M.D., D.Sc. (Medicine), Professor
俄罗斯联邦, Санкт-Петербург参考
- Udalov YuD, Gordienko AV, Samoilov AS, et al. Psychoemotional stress in somatically burdened oncological surgery patients as one of the factors of postoperative complications. Research’n Practical Medicine Journal. 2018;5(3):117–125. (In Russ.) doi: 10.17709/2409-2231-2018-5-3-12
- Doundoua DP, Staferov АV, Sorokin АV, Kedrova АG. Cardiooncology: chemotherapy drugs and radiation therapy impact on cardiovascular system. Journal of Clinical Practice. 2016;4(28):41–48. (In Russ.)
- Tsygan NV, Andreev RV, Ryabtsev AV, et al. Perioperative stroke and postoperative cerebral dysfunction: epidemiology, pathogenesis features, current possibilities of intensive cerebroprotection in the preoperative “preventive” window. Bulletin of the Russian Military Medical Academy. 2019; S3:159–161(In Russ.)
- Ng JLW, Chan MT, Gelb AW. Perioperative stroke in noncardiac, nonneurosurgical surgery. Anesthesiology. 2011;115(4):879–890. doi: 10.1097/aln.0b013e31822e9499
- Dardiotis E, Aloizou AM, Markoula S, et al. Cancer-associated stroke: Pathophysiology, detection and management (Review). Int J Oncol. 2019;54(3):779–796. doi: 10.3892/ijo.2019.4669
- Kuanova LB, Mendykulov SE, Daribaeva SA. Preventive steps to reduce the risk of stroke after cardiac surgery. The Journal of Neuroscience of B.M. Mankovsky. 2016;4(1):24–27. (In Russ.)
- Roughead T, Chui J, Gelb AW, et al. Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery. Can J Anesth. 2020;67(1):13–21. doi: 10.1007/s12630-019-01474-w
- Devereaux PJ, Yang H, Yusuf S, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008;371(9627):1839–1847. doi: 10.1016/s0140-6736(08)60601-7
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