电邮这篇文章 Species diversity of vaginal lactobacilli in norm and in dysbiotic states
- 作者: Budilovskaya O.V1, Shipitsyna E.V1, Gerasimova E.N1, Safronova M.M2, Savicheva A.M1
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隶属关系:
- FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott”
- North-western State Medical University named after I.I.Mechnikov
- 期: 卷 66, 编号 2 (2017)
- 页面: 24-32
- 栏目: Articles
- URL: https://journal-vniispk.ru/jowd/article/view/6353
- DOI: https://doi.org/10.17816/JOWD66224-32
- ID: 6353
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Introduction. In healthy women of reproductive age, the vaginal microflora is represented mainly by lactobacilli. They provide a barrier function, preventing the propagation of opportunistic pathogens and the colonization of the vagina by pathogenic microorganisms. It is shown that the lactobacillary microflora of the vagina is very diverse, but not all species of lactobacilli can provide reliable protection of the female organism.
Objective: to characterize the species and quantitative composition of vaginal lactobacilli of women of reproductive age in norm and in dysbiosis.
Material and methods. The study involved 123 patients from polyclinic departments of the D.O. Ott Reasearch Institute of Obstetrics, Gynecology and Reproductology. For analysis of clinical material (vaginal discharge) for lactobacilli and other microorganisms, quantitative real-time PCR was used.
Results. The most common types of lactobacilli are Lactobacillus jensenii, L. Iners, L. crispatus, L. vaginalis and L. gasseri. Species diversity of lactobacilli (detection of ≥2 species) is observed much more often in women with physiological microbiocenosis than in women with vaginal dysbiosis. Our study confirms that L. crispatus is the dominant species of the vaginal biotope of healthy women, while in dysbiosis the species L. gasseri and L. Iners are most often identified.
作者简介
Olga Budilovskaya
FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott”
编辑信件的主要联系方式.
Email: o.budilovskaya@gmail.com
Researcher, Laboratory of Microbiology
俄罗斯联邦, Saint Petersburg, RussiaElena Shipitsyna
FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott”
Email: shipitsyna@inbox.ru
Senior Researcher, Laboratory of Microbiology
俄罗斯联邦, Saint Petersburg, RussiaEkaterina Gerasimova
FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott”
Email: iagmail@ott.ru
Researcher, Laboratory of Microbiology
俄罗斯联邦, Saint Petersburg, RussiaMargarita Safronova
North-western State Medical University named after I.I.Mechnikov
Email: kafedra.pro@mail.ru
MD, Professor, Head of the Department of Women’s Reproductive Health
俄罗斯联邦, Saint Petersburg, RussiaAlevtina Savicheva
FSBSI “The Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott”
Email: savitcheva@mail.ru
Head of Laboratory of Microbiology
俄罗斯联邦, Saint Petersburg, Russia参考
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