Free radical reactions in the development of combined hyperplastic processes in female reproductive system organs
- 作者: Niauri D.A.1, Chepur S.V.1, Popov Е.N.1, Charitonov К.P.1, Kuznetsova I.V.1
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隶属关系:
- Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
- 期: 卷 54, 编号 2 (2005)
- 页面: 31-35
- 栏目: Original study articles
- URL: https://journal-vniispk.ru/jowd/article/view/81797
- DOI: https://doi.org/10.17816/JOWD81797
- ID: 81797
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Intact myometrium specimen, received from 56 women of reproductive age during surgical interventions. There were 30 women with combined hyperplastic processes in the reproductive system organs (uterine myoma, endometrium hyperplasia, adenomyosis, benign ovarian tumors, mastopathy, background cervical pathology), and in 26 cases solitary uterine myoma was found. At infrared spectrometry of the lyofilized myometrium, taken from patients with combined proliferation foci, a stable peak with wave number 3500 sm—1 was found, which reflects the accumulation of molecules with oxidized OH—groups and a change in proportion of OH—/NH—containing molecules. At the study of the myometrium of patients with single myoma focus the described peak was absent. The acquired data suggests, that combined benign hyperplasias in the reproductive system organs are accompanied by the oxidative stress cascade reactions, characterized by uncontrollable production of free radicals and/or insufficiency of antiradical protection mechanisms.
作者简介
D. Niauri
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
编辑信件的主要联系方式.
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
S. Chepur
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
Е. Popov
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
К. Charitonov
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
I. Kuznetsova
Research Institute of Obstetrics, Gynecology and Reproductology named after D.O. Ott
Email: info@eco-vector.com
俄罗斯联邦, Saint Petersburg
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