Modified Antiproteinase Hemosorbent
- Авторы: Valuev I.L.1, Valuev L.I.1, Vanchugova L.V.1, Obydennova I.V.1
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Учреждения:
- Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
- Выпуск: Том 55, № 1 (2019)
- Страницы: 21-24
- Раздел: Article
- URL: https://journal-vniispk.ru/0003-6838/article/view/152762
- DOI: https://doi.org/10.1134/S0003683819010174
- ID: 152762
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Аннотация
A method to increase the thromboresistance of the biospecific antiproteinase hemosorbent was suggested based on simultaneous immobilization of duck egg ovomucoid and blood anticoagulant—heparin or hirudin—in the bulk of polyacrylamide hydrogel. It was demonstrated that modification of the hemosorbent with hirudin resulted in a significant increase of its compatibility with blood with simultaneous preservation of high capacity with regards to serine proteinases.
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Об авторах
I. Valuev
Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Автор, ответственный за переписку.
Email: valuev@ips.ac.ru
Россия, Moscow, 119991
L. Valuev
Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Email: valuev@ips.ac.ru
Россия, Moscow, 119991
L. Vanchugova
Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Email: valuev@ips.ac.ru
Россия, Moscow, 119991
I. Obydennova
Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences
Email: valuev@ips.ac.ru
Россия, Moscow, 119991
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