Correction of Immunoendocrine Disorders in Patients with Ischemic Heart Disease Using Low-intensity Microwave Therapy

Abstract

The article considers the possibility of correcting immunoendocrine disorders in patients with ischemic heart disease using low-intensity microwave radiation at a frequency of 1 GHz. The study showed that the Aquaton device for low-intensity microwave therapy could be used to stimulate production of bradykinin, NO, IL-24, antioxidants, and soluble tumor necrosis factor-alpha receptor II by whole blood cells. Exposure to microwave irradiation was accompanied by a decrease in the caspase-1 content in mononuclear leukocytes with a simultaneous increase in the nuclear transcription factor NFκB level, promoting thereby normalization of the subclinical inflammatory process and correction of endothelial dysfunction.