Regeneration of Articular Cartilage in Experimental Osteoarthrosis after Injection of a Complex Polyacrylamide-Hyaluronic Gel


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Abstract

The regenerative capacity of articular cartilage was assessed after injection of Matricin polyacrylamide-hyaluronic gel into the knee joints of nine rabbits with a model of osteoarthrosis. Matricin decreased dystrophic and destructive changes in articular cartilage previously induced by exposure to papain solution and produced a significant increase in the regenerative capacity of the damaged hyaline cartilage.

About the authors

V. V. Zar

M. F. Vladimirsky Moscow Regional Research and Clinical Institute

Author for correspondence.
Email: vzar@list.ru
Russian Federation, Moscow

A. B. Shekhter

Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: vzar@list.ru
Russian Federation, Moscow

E. N. Sukhanov

Moscow Regional Hospital for War Veterans

Email: vzar@list.ru
Russian Federation, Zhilino, Moscow Region

M. V. Zar

Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Email: vzar@list.ru
Russian Federation, Moscow

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