Maintenance of the Cardiovascular Function in a Deeply Cooled Homeothermic Organism by Physiological Methods without External Rewarming


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Abstract

Gradual cooling of homeothermic organisms is followed by slowing and arrest of breathing and heart contractions. During deep cooling, even relatively slight artificial ventilation decreases the lower temperature limit of life (by 4.5-5°C) and provides minimum oxygen supply to the heart and whole body. This allows us to restore cardiovascular function and prevent animal death after lethal cooling without external warming.

About the authors

K. P. Ivanov

I. P. Pavlov Institute of Physiology, Russian Academy of Sciences

Author for correspondence.
Email: kpivanov@nc2490.spb.edu
Russian Federation, St. Petersburg

N. K. Arokina

I. P. Pavlov Institute of Physiology, Russian Academy of Sciences

Email: kpivanov@nc2490.spb.edu
Russian Federation, St. Petersburg

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