Отправить статью по E-mail Dose Dependence of the Anticoagulant Effect of Intravenously Administered Cellulose Sulfate
- Авторы: Drozd N.N.1, Kuznetsova S.A.2, Kalinina T.B.1, Vasilieva N.Y.2
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Учреждения:
- Hematological Research Center, Ministry of Health of the Russian Federation
- Institute of Chemistry and Chemical Technology, Siberian Branch of the Russian Academy of Sciences
- Выпуск: Том 160, № 6 (2016)
- Страницы: 767-770
- Раздел: Article
- URL: https://journal-vniispk.ru/0007-4888/article/view/236935
- DOI: https://doi.org/10.1007/s10517-016-3305-6
- ID: 236935
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Аннотация
Experiments on rabbits showed that increasing the dose of intravenously administered cellulose sulfate from wheat straw (dynamic viscosity 3.4 cP, sulfur content 14.1%) increased plasma clotting time in some coagulation tests and plasma anticoagulant activity. When cellulose sulfate was administered in the dose of 1 mg/kg, plasma clotting time in the presence of the anticoagulant (5 min after administration) was ~3-fold higher than after saline administration.
Об авторах
N. Drozd
Hematological Research Center, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: nndrozd@mail.ru
Россия, Moscow
S. Kuznetsova
Institute of Chemistry and Chemical Technology, Siberian Branch of the Russian Academy of Sciences
Email: nndrozd@mail.ru
Россия, Krasnoyarsk
T. Kalinina
Hematological Research Center, Ministry of Health of the Russian Federation
Email: nndrozd@mail.ru
Россия, Moscow
N. Vasilieva
Institute of Chemistry and Chemical Technology, Siberian Branch of the Russian Academy of Sciences
Email: nndrozd@mail.ru
Россия, Krasnoyarsk
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