Отправить статью по E-mail Effect of New Antiviral Agent Camphecin on Behavior of Mice
- Авторы: Babina A.V.1, Lavrinenko V.A.1, Yarovaya O.I.1,2, Salakhutdinov N.F.1,2
-
Учреждения:
- Novosibirsk National Research State University
- N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Division of Russian Academy of Sciences
- Выпуск: Том 162, № 3 (2017)
- Страницы: 346-348
- Раздел: Pharmacology and Toxicology
- URL: https://journal-vniispk.ru/0007-4888/article/view/238192
- DOI: https://doi.org/10.1007/s10517-017-3612-6
- ID: 238192
Цитировать
Открытый доступ
Доступ предоставлен
Только для подписчиков
Аннотация
We studied the effect of camphecin (1,7,7-trimethylbicyclo[2.2.1]heptan-2-ylidene-aminoethanol) on mouse behavior in the open-field test. Camphecin possesses antiviral activity and inhibits viral replication, but its influence on the nervous system is poorly studied. Single camphecin injection produced no significant changes in behavioral patterns. Chronic camphecin administration (5 times over 2 weeks) to mice of different strains had no significant influence on open field behavior (motor, exploratory activity, anxiety, emotional state and vegetative functions). The findings are discussed in the context of neutral influence of camphecin on animal behavior.
Об авторах
A. Babina
Novosibirsk National Research State University
Email: igor@academ.org
Россия, Novosibirsk
V. Lavrinenko
Novosibirsk National Research State University
Автор, ответственный за переписку.
Email: igor@academ.org
Россия, Novosibirsk
O. Yarovaya
Novosibirsk National Research State University; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Division of Russian Academy of Sciences
Email: igor@academ.org
Россия, Novosibirsk; Novosibirsk
N. Salakhutdinov
Novosibirsk National Research State University; N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Division of Russian Academy of Sciences
Email: igor@academ.org
Россия, Novosibirsk; Novosibirsk
Дополнительные файлы
