Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices

S. N. Kolbaev; O. P. Aleksandrova; I. N. Sharonova; V. G. Skrebitsky

doi:10.1007/s10517-018-3983-3

Effect of Noopept on Dynamics of Intracellular Calcium in Neurons of Cultured Rat Hippocampal Slices

Authors: Kolbaev S.N.¹, Aleksandrova O.P.¹, Sharonova I.N.¹, Skrebitsky V.G.¹
Affiliations:
1. Research Center of Neurology
Issue: Vol 164, No 3 (2018)
Pages: 330-333
Section: Article
URL: https://journal-vniispk.ru/0007-4888/article/view/239579
DOI: https://doi.org/10.1007/s10517-018-3983-3
ID: 239579

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Abstract

A neuroprotective and nootropic drug Noopept increased the frequency of spontaneous calcium transients in neurons of CA1 radial layer in cultured rat hippocampal slices. In contrast, the drug exerted no significant effect on intracellular calcium concentration and its dynamics in neurons of hippocampal CA1 pyramidal layer.